Welcome to the TIGA Center
Tissue Imaging and Analysis Center
The TIGA Center is a cooperative project which started in 2007 at the University Heidelberg with the goal of establishing a bioinformatics platform dedicated to the quantitative analysis and modeling of tissues. A strong emphasis is placed on clinically relevant research projects.
At the heart of the TIGA’s technology platform are automated microscopic scanners for whole slide imaging of glass slides. By integrating such imaging systems in a technical pipeline ranging from organotypic in vitro cell cultures to computational tissue modeling the TIGA generates a wealth of yet unexploited clinically highly relevant tissue data.
Our technical pipeline now integrates:
- In vitro tissue modeling
- Tissue sample processing
- Automated whole slide imaging (virtual microscopy)
- Quantitative image processing
- In-silico Tissue Modeling.
Within its research network the TIGA provides the expertise to participate in major projects to tackle selected critical questions in human biology and disease.
News
Tiga News Section
12.04.2011
TIGA and Biocomplexity Institute, Indiana University offer a joint workshop at the ICSB 2011
Standardized Model Description Language for Multi-Cellular Simulations
We proudly annouce that the TIGA will offer a workshop at the ICSB 2011 together with James Galzier and his team from the Biocomplexity Institute, Indiana University.
Please visit our workshop website for further information.
The workshop registration is now open!
12.07.2010
Presentations and photos online
The presentations and the photos of the 2nd European Workshop on Tissue Imaging and Analysis are now available on our workshop website.
24.05.2010
TIGA Workshop 2010: Open places still available
Open places for the workshop are still available until June 18th.
29.03.2010
2nd European Workshop on Tissue Imaging and Analysis - Registration is now open
The registration for the 2nd European Workshop on Tissue Imaging and Analysis is now open. The workshop will take place on June 25-26, 2010 in the BIOQUANT building in Heidelberg. For more information please see our workshop website.
The workshop will include a poster session. Please submit your abstract while registering for the workshop using the registration form.
08.03.2010
2nd European Workshop on Tissue Imaging and Analysis
The 2nd European Workshop on Tissue Imaging and Analysis will be on June 25-26, 2010 in the BIOQUANT building in Heidelberg.
Further details will be posted on our website within the next days.
04.03.2010
TIGA original paper published in Cellular Oncology
Grabe N, Lahrmann B, Pommerencke T, von Knebel Doeberitz M, Reuschenbach M, Wentzensen N. A virtual microscopy system to scan, evaluate and archive biomarker enhanced cervical cytology slides. Cell Oncol. 2010;32(1-2):109-19.
Please click here to view the article in pubmed.
23.11.2009
TIGA original paper published in PLoS One
Halama N, Zoernig I, Spille A, Westphal K, Schirmacher P, Jaeger D, Grabe N. Estimation of immune cell densities in immune cell conglomerates: an approach for high-throughput quantification. PLoS One. 2009 Nov 16;4(11):e7847.
Please click here to view the article in pubmed.
24.08.2009
Report of TIGA Workshop 2009 appeared in Virchows Archiv
Grabe N, Schirmacher P. From virtual microscopy to systems pathology: a meeting report of the 1st European workshop on tissue imaging and analysis, Heidelberg, Germany, 13-14 February 2009. Virchows Arch. 2009 Aug;455(2):193-6.
Please click here to view the article in pubmed.
15.08.2009
TIGA original paper published in Bioinformatics
Our article "Modeling multi-cellular behavior in epidermal tissue
homeostasis via finite state machines in multi-agent systems" was
published on August 15th in Bioinformatics, Oxford Journals.
The supplementary material of this paper is available here.
Please click here to view the article in pubmed.
