Tissue Modelling

Tissue Modelling Section

The picture below shows the Episim Modeller and the Episim Simulator which allow the specification and the subsequent interactive simulation of Cell Behavioral Models of epithelial tissues.

Cellular behavior is modeled with process diagrams using deterministic and / or stochastic model elements. The Episim Modeller was developed in order to enable users to build their own cell behavioral model in a graphical way. No specific programming skills are needed. The opportunities of the Episim Modeller are presented in short video tutorials.

Episim Video Tutorials

• Tutorial 1: Introduction to Episim Modeller (flash movie) (avi file)
• Tutorial 2: Model Validation (flash movie) (avi file)
• Tutorial 3: Model Transformation into Java Code (flash movie) (avi file)
• Tutorial 4: Introduction to Episim Simulator (flash movie) (avi file)
• Tutorial 5: Using the available default charts in Episim Simulator (flash movie) (avi file)
• Tutorial 6: Demonstration of different cell cycle models in Episim Simulator (flash movie) (avi file)
• Tutorial 7: Episim Modeller - Steps to create an own model part I (create a new model project and model file, arrangement of the modelling windows) (flash movie) (avi file)
• Tutorial 8: Episim Modeller - Steps to create an own model part II (define necessary cell types, global tissue parameters and cell properties) (flash movie) (avi file)
• Tutorial 9: Episim Modeller - Steps to create an own model part III (using different kinds of model elements, definition of transitions) (flash movie) (avi file)
• Tutorial 10: Episim Modeller - Steps to create an own model part IV (definition of action strings, conditions and choices using the Variable-Sheet Editor and the Function Library) (flash movie) (avi file)